Browsing by Author "Kallioniemi, Olli"

Now showing items 1-2 of 2

    • Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response 

      Jernström, Sandra Johanna; Hongisto, Vesa; Leivonen, Suvi-Katri; Due, Eldri Undlien; Tadele, Dagim Shiferaw; Edgren, Henrik; Kallioniemi, Olli; Perälä, Merja; Mælandsmo, Gunhild; Sahlberg, Kristine Kleivi (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-21)
      Background<br> Approximately 15%–20% of all diagnosed breast cancers are characterized by amplified and overexpressed HER2 (= ErbB2). These breast cancers are aggressive and have a poor prognosis. Although improvements in treatment have been achieved after the introduction of trastuzumab and lapatinib, many patients do not benefit from these drugs. Therefore, in-depth understanding of the mechanisms ...

    • Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23–24, 2023 

      Ringborg, Ulrik; von Braun, Joachim; Celis, Julio; Baumann, Michael; Berns, Anton; Eggermont, Alexander; Heard, Edith; Heitor, Manuel; Chandy, Mammen; Chen, Chien-Jen; Costa, Alberto; De Lorenzo, Francesco; De Robertis, Edward M.; Dubee, Frederick Charles; Ernberg, Ingemar; Gabriel, Mariya; Helland, Åslaug; Henrique, Rui; Jönsson, Bengt; Kallioniemi, Olli; Korbel, Jan; Krause, Mechthild; Lowy, Douglas R.; Michielin, Olivier; Nagy, Peter; Oberst, Simon; Paglia, Vincenzo; Parker, M. Iqbal; Ryan, Kevin; Sawyers, Charles L.; Schüz, Joachim; Silkaitis, Katherine; Solary, Eric; Thomas, David; Turkson, Peter; Weiderpass Vainio, Elisabete; Yang, Huanming (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-22)
      Analyses of inequalities related to prevention and cancer therapeutics/care show disparities between countries with different economic standing, and within countries with high Gross Domestic Product. The development of basic technological and biological research provides clinical and prevention opportunities that make their implementation into healthcare systems more complex, mainly due to the growth ...